Impact of Multimodal Therapy on Margin Status on Overall Survival for Patients Undergoing Adrenalectomy for Localized Adrenocortical Carcinoma

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy that arises from the adrenal cortex. It challenging disease to manage due its rarity, variable presentation, lack of effective systemic therapy options. Objectives: The main objective study find impact multimodal on margin status overall survival for patients undergoing adrenalectomy localized adrenocortical carcinoma. Material methods: aim this was investigate in who underwent between March 2022 till November at single tertiary care center. Results: Based analysis 300 2000 center, found may improve patient population. Of included study, 150 received (adjuvant radiation and/or chemotherapy) observation after surgery. median follow-up time 48 months. Conclusion: In conclusion, findings suggest be an treatment option Multimodal associated with significantly higher rate compared alone.